The reaction of intramolecular cyclization of 1,3-butadiene oxide to 2,5-dihydrofuran was studied using various catalytic systems. It was found that the reaction occurs most effectively in the presence of zinc chloride; lithium iodide; and solvents, such as N-methylpyrrolidone and dimethylformamide. The influence of various factors on the 1,3-butadiene cyclization reaction in these solvents was studied. It was shown that tetrahydrofuran could be obtained in almost quantitative yield by hydrogenating 2,5-dihydrofuran on an industrial Pd/Al2O3 catalyst.