The chemical, pharmaceutical and other related process industries are characterized by inherently hazardous processes and activities. To ensure that considered risk management decisions are made it is essential that organizations have the ability to rank the risk profiles of their assets and operations. Current industry risk ranking techniques are biased toward the assessment of the risk potential of the asset or operation. Methodologies used to assess these risks tend to be engineering-based and include, for example, hazard identification and event rate estimation techniques. Recent research has associated lagging safety performance indicators with metrics of organizational safety climate. Despite the evidence suggesting their potential usefulness, organizational climate metrics have not yet been exploited as a proactive safety, health and environmental performance indicator or as an aid to relative risk ranking. This paper summarizes research that successfully produced a statistical model of organizational climate and its relationship to site significant injury frequency rates, allowing the relative risk ranking of sites based upon organizational climate metrics. The responses to an industrial organizational survey are examined for a pharmaceutical company's sites in the United Kingdom, Sweden and the United States. Projection to Latent Structures Analysis is performed on the survey responses. The resultant models are shown to be able to accurately model the site significant injury frequency rates. The organizational climate metrics; that discriminate between the safety performance levels of different sites are identified.