화학공학소재연구정보센터
Przemysl Chemiczny, Vol.86, No.8, 743-746, 2007
The improvements in the synthesis of ACE inhibitors. Preparation of trandolapril, ramipril and quinapril
A new synthesis and technol. process for the prepn. of ACE inhibitors (trandolapril, ramipfil and quinapril hydrochloride) were developed. The purifn. of trandolapril and ramipril was improved by use a simple recrystn. of their diastereomers.