Chromatog. methods for detn. pramipexole and its two impurities: S(-)-4,5,6,7-tetrahydrobenzothiazol-2,6-diamine and (S)(-)-4,5,6,7-tetrahydro-N-6,N(6)dipropylbenzothiazole-2,6-diamine dihydrochloride monohydrate in com. product were developed. Two HPLC methods were compared. The partial validation was done. The specificity and selectivity, linearity, detection limit, quantitation limit and precision were detd.