Przemysl Chemiczny, Vol.91, No.3, 314-318, 2012
Application of accelerator mass spectrometry (AMS) in early drug development. Part 1. Background and procedures
A review, with 40 refs., and fundamentals of combined applications of linear accelerator and high resolution mass spectrometer for detection of org. compds. containing suitable C-14 labels in femtomol concns. for studying pharmacokinetic parameters and metabolic fate of drugs from single sub-pharmacolog. dose.