This work investigates the effect of thermophoresis and chemical reaction on heat and mass transfer in hydromagnetic micropolar fluid flow over an inclined permeable plate with constant heat flux and non-uniform heat source/sink in the presence of thermal radiation. It is assumed that the transverse magnetic field is a function of the distance from the origin. The analysis accounts for both temperature dependent fluid viscosity and thermal conductivity. Using the similarity transformation, the governing system of equations are transformed into non-linear ordinary differential equations and are solved numerically using symbolic software MATHEMATICA. Numerical results for the velocity, microrotation, temperature and species concentration as well as for the skin friction, heat and mass transfer are obtained and displayed graphically for pertinent parameters to show interesting aspects of the solution. (C) 2012 Elsevier Ltd. All rights reserved.