Journal of the American Chemical Society, Vol.134, No.46, 18936-18939, 2012
Cobalt-Catalyzed Asymmetric 1,6-Addition of (Triisopropylsilyl)-acetylene to alpha,beta,gamma,delta-Unsaturated Carbonyl Compounds
Asymmetric addition of (triisopropylsilyl)-acetylene to alpha,beta,gamma,delta-unsaturated carbonyl compounds took place in the presence of a cobalt/Duphos catalyst to give the 1,6-addition products in high yields with high regio- and enantioselectivity.