On July 24th, 2010, several explosions and fires devastated a hydrocarbon processing plant in Kharg Island, Iran. Four workers were killed and many others were severely injured. The plant became out of service for 80 days. The way the accident happened and its sequence was representing as a domino accident. In this paper, events leading up to the disaster have been analyzed in details. Graphic presentation techniques such as Fish Bone Analysis and Event Sequence Diagram (ESD) have been utilized to enhance the understanding of the accident mechanism. Finally major lessons learnt from this domino accident have been addressed. (C) 2012 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.