Dynamic spontaneous imbibition (DSI) plays an important role in oil reservoir characterization. Conventional equations used to characterize DSI consider neither interfacial coupling effects (ICE) nor variable inlet saturation (S*) for DSI. Yazzan et al. (Transp Porous Media 87(1):309-333, 2011a; 86(3):705-717, 2011b) developed a set of equations, and a numerical solution scheme, to take into account ICE and variable S* for DSI. Based on these, a graphical user interface (GUI) simulator was built. A sensitivity analysis has been conducted to study the effect of the fluid and rock properties on DSI. The results reveal that including a variable S* has no significant impact; however, neglecting ICE results in an overestimation of the imbibition flow rate. Moreover, it is shown that the capillary and relative permeability curves determine the type of frontal advance, and that the imbibition recovery is proportional to the square root of time.