Reactants, weak molecular complexes, transition states, and products for the H-, Cl-, and I-abstraction channels in the reaction of OH radicals with chloroiodomethane CH2ICI as well as the energy profiles at 0 K have been determined using high-level all-electron ab initio methods. The results showed that all-electron DK-CCSD(T)/ANO-RCC approach performed very well in predicting the reactivity of iodine. In terms of activation enthalpy at 0 K, the energy profile for the Cl-abstraction showed that this reaction pathway is not energetically favorable in contrast to the two other channels (H- and I-abstractions), which are competitive. The H-abstraction was strongly exothermic (-87 kJ mol(-1)), while the I-abstraction was modestly endothermic (11.8 kJ mol(-1)). On the basis of our calculations including the following corrections to the potential energies: basis set saturation, valence and core- valence electron correlation, relativistic effects, spin-adaptation, vibration contributions, and tunneling corrections, rate constants were predicted using canonical transition state theory over the temperature range 250-500 K for each abstraction pathway. The overall rate constant at 298 K was estimated to be 4.29 X 10(-14) and 5.44 X 10(-14) cm(3) molecule(-1) s(-1) for complex and direct abstraction mechanisms, respectively. In addition, the overall rate constant computed at 277 K was used in the estimation of the atmospheric lifetime for CH2ICl. On the basis of our theoretical calculations, the atmospheric lifetime for the OH removal process is predicted to be close to I year. In terms of atmospheric lifetime, the OH reaction is not competitive with the Cl reaction and photolysis processes.