The catalytic properties of zeolites modified with titanium or with titanium and sulfur have been studied in the conversion of dimethyl ether (DME) to lower olefins and high-octane hydrocarbon components of gasoline. Using ammonia temperature-programmed desorption, it has been shown that the introduction of titanium and sulfur leads to an increase in the number of medium-strength acid sites and superacid sites. The effect of the operating parameters of the DME conversion to synthetic hydrocarbons has been analyzed, and changes in activity and selectivity for target products in oxidative regeneration have been studied.