화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.19, No.3, 721-726, May, 2013
DOI10.1016/j.jiec.2012.10.014  Export Citation
Design of ionic liquid 1,3-disulfonic acid imidazolium hydrogen sulfate as a dual-catalyst for the one-pot multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles
Mohammad Ali Zolfigol†, Ardeshir Khazaei†, Ahmad Reza Moosavi-Zare†, Abdolkarim Zare1, Zhila Asgari, Vahid Khakyzadeh, and Alireza Hasaninejad2
  • Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, Iran
  • 1Department of Chemistry, Payame Noor University, PO Box 19395-4697 Tehran, Iran
  • 2Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran
E-mail:, ,
Novel ionic liquid 1,3-disulfonic acid imidazolium hydrogen sulfate {[Dsim]HSO4} efficiently catalyzes the synthesis of 1,2,4,5-tetrasubstituted imidazoles via the one-pot multi-component condensation of benzyl with aldehydes, primary amines and ammonium acetate at 90 ℃ under solvent-free conditions. Dual hydrogen-bond donors can be used to direct the assembly of this catalyst and the efficiency of it.
Keywords:1,3-Disulfonic acid imidazolium hydrogen;sulfate {[Dsim]HSO4};Ionic liquid;Imidazole;1,2,4,5-Tetrasubstituted imidazoles;Multi-component reaction;Solvent-free
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