This study investigates the boundary layer stagnation point flow of a nanofluid past a permeable flat surface with Newtonian heating. The model used for the nanofluid is the one that incorporates the combined effects of Brownian motion and thermophoresis. Using a local similarity variable, the governing nonlinear partial differential equations have been transformed into a set of coupled nonlinear ordinary differential equations, which are solved numerically by applying the shooting iteration technique together with a fourth-order Runge-Kutta integration scheme. Graphical results for the dimensionless velocity, temperature, and nanoparticle concentration distributions are shown for various values of the six thermophysical parameters controlling the flow regime: Prandtl number Pr, Lewis number Le, convection Biot number Bi, the Brownian motion parameter Nb, the thermophoresis parameter Nt, and the suction/injection parameter . The expressions for the local skin friction, reduced Nusselt number, and reduced Sherwood number were obtained numerically and are discussed quantitatively.