화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.19, No.4, 1280-1288, July, 2013
DOI10.1016/j.jiec.2012.12.029  Export Citation
Antibacterial activity of dithiothreitol reduced graphene oxide
Sangiliyandi Gurunathan†, Jae Woong Han, Ahmed Abdal Dayem, Vasuki Eppakayala, Mi-Ryung Park, Deug-Nam Kwon, and Jin-Hoi Kim†
  • Department of Animal Biotechnology, Konkuk University, 1 Hwayang-Dong, Gwangin-gu, Seoul 143-701, Republic of Korea
E-mail:,
A green and simple approach is described for the large scale synthesis of reduced graphene oxide (rGO). The transition of graphene oxide (GO) into graphene was confirmed using various analytical techniques. Raman spectroscopy data indicate the partial removal of oxygen-containing functional groups from the surface of GO and formation of graphene. X-ray diffraction (XRD) was used to investigate the crystallinity of graphene nanosheets. The antibacterial activity of GO and rGO was evaluated using cell viability, reactive oxygen species (ROS) production and DNA fragmentation assays. The results suggest that GO and rGO possessed an excellent antimicrobial activity against Escherichia coli.
Keywords:Graphene oxide;Reduced graphene oxide;Dithiothreitol;E. coli;UV-visible spectroscopy;Raman spectroscopy
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