The Taylor dispersion method has been used to determine diffusion coefficients of N-methylpyrrolidone, 2-methyl-2,4-pentanediol, glycerol, 1,3-butanediol, and 1,2,6-hexanetriol at infinite dilution in water and of water, glycerol, and 2-methyl-2,4-pentanediol at infinite dilution in N-methylpyrrolidone. The temperature has been varied between 298 and 348 K.