In this communication, we describe the development of a new plasma/flame facility and burner platform that appears promising for directly investigating the effects of high-voltage, nanosecond-duration, repetitively pulsed plasma discharges on moderate- and high-temperature reaction chemistry. Such a configuration is ideal for identifying key processes and key species that can alter fuel oxidation, hydrocarbon intermediate formation, and radical formation/heat-release under combusting conditions. Initial results using emission spectroscopy demonstrate that the excited-state species such as OH*, CH*, and are significantly enhanced in the presence of repetitive nanosecond pulse discharges. This new plasma-flame facility also lends itself to kinetic modeling due to its simple quasi-one-dimensional geometry and uniformity of the nanosecond pulse discharge.