Chemistry Letters, Vol.42, No.7, 753-755, 2013
Synthesis of Spirooxindoles from Carbamoyl Chlorides via Cyclopropyl Methine C(sp(3))-H Activation Using Palladium Catalyst
The synthesis of spirooxindoles fused with cyclopropanes from carbamoyl chlorides, via methine C(sp(3))-H activation, is reported. The regioselectivity of C-H activation in the presence of competitive C-H bonds at the appropriate position was investigated under the optimized conditions.