Journal of Structural Biology, Vol.183, No.3, 389-393, 2013
Selection and orientation of different particles in single particle imaging
The short pulses of X-ray free electron lasers can produce diffraction patterns with structural information before radiation damage destroys the particle. The particles are injected into the beam in random orientations and they should be identical. However, in real experimental conditions it is not always possible to have identical particles. In this paper we show that the correlation maximization method, developed earlier, is able to select identical particles from a mixture and find their orientations simultaneously. (c) 2013 Elsevier Inc. All rights reserved.
Keywords:X-ray free electron lasers;Single particle diffraction;Single molecule diffraction;Orientation