Removal of toxic heavy metal ions from environmental and biological systems is important, but the use of commercially available heavy metal adsorbents is complicated by the need for specific pretreatment steps. We chose to study human hair treated with perm lotion as a heavy metal adsorbent because it is readily available and contains a large number of sulfur atoms for strong coordination to heavy metal ions. The optimal pH of adsorption by perm lotiontreated human hair was 4.16, which was slightly higher than the isoelectric point (pI) of the hair. The maximum removal ratio at pH 4.16 was 88.5% for a 50 ppm Cu2+ solution, and 96.79% for a 50 ppm Pb2+ solution. Almost 90% of the Pb2+ was removed from a 120 ppm Pb2+ solution. The perm-lotion-treated human hair was a cation-selective adsorbent.