Korea-Australia Rheology Journal, Vol.26, No.2, 191-198, May, 2014
Yield shear stress and disaggregating shear stress of human blood
E-mail:,
This review presents two distinct rheological parameters of blood that have the potential to indicate blood circulation adequacy: yield shear stress (YSS) and disaggregating shear stress (DSS). YSS and DSS reflect the strength of red blood cell (RBC) aggregation in suspension under static and dynamic conditions, respectively. YSS, defined as the critical stress to disperse RBC aggregates under static conditions, was found to be dependent upon hematocrit, fibrinogen, and red cell deformability, but not temperature. DSS, defined as the minimum shear stress to disperse RBC aggregates under dynamic conditions, is dependent upon fibrinogen, red cell deformability, and temperature but not hematocrit. Owing to recent advances in measurement technology, these two parameters can be easily measured, and thus, their clinical significance in blood circulation
can be verified.
- Alexy T, Wenby RB, Pais E, Goldstein LJ, Hogenauer W, Meiselman HJ, Biorheology, 42, 237 (2005)
- Baskurt OK, Boynard M, Cokelet GC, Connes P, Cooke BM, Forconi S, Liao F, Hardeman MR, Jung F, Meiselman HJ, Nash G, Nemeth N, Neu B, Sandhagen B, Shin S, Thurston G, Wautier JL, Clin. Hemorheol. Microcirc., 42, 75 (2009)
- Baskurt OK, Meiselman H, Biorheology, 34, 235 (1997)
- Baskurt OK, Neu B, Meiselman H, Red blood cell aggregation, CRC Press, 9-25 (2012)
- Boursachs RM, Wenby RM, Meiselman HJ, Clinical Hemorheology, 9, 1 (1989)
- Casson N, A flow equation for pigment-oil suspension of the printing ink type, in: Rheology of Disperse System, C.C. Mills ed., Pergamon Press, New York, 84-104 (1959)
- Chien S, Sung LA, Kim S, Burke AM, Microvasc. Res., 13, 327 (1977)
- Chien S, Usami S, Taylor HM, Lundberg JL, Gregersen MI, J. Appl. Physiol., 21, 81 (1966)
- Chmiel H, Biorheology, 11, 87 (1974)
- Cokelet GR, Merrill EW, Gilliland ER, Trans. Soc. Rheol., 7, 303 (1963)
- Cokelet GC, Meiselman H, In: Micro- and macrorheological properties of blood in Handbook of Hemorheology and Hemodynamics, Baskurt OK, Hardeman MR, Rampling MW, Meiselman HJ eds., IOS Press, Amsterdam, The Netherlands, 45-71 (2007)
- Fedosov DA, Pan W, Caswell B, Gompper G, Karniadakis GE, PNAS, 108, 11772 (2011)
- Fahraus R, Acta Med Scand., 161, 151 (1958)
- Hardeman MR, Dobbe JG, Ince C, Clin. Hemorheol. Microcirc., 25, 1 (2001)
- Hou JX, Shin SH, Korea-Aust. Rheol. J., 20(4), 253 (2008)
- Kim J, Chung HM, Cho MH, Lee BJ, Karimi A, Shin S, Clinical. Hemorheol. Microcirc., 55, 101 (2013)
- Kim S, Cho YI, Jeon AH, Hogenauer B, Kensey KR, J. Non-Newton. Fluid Mech., 94(1), 47 (2000)
- Kim S, Cho YI, Hogenauer WN, Kensey KR, J. Non-Newton. Fluid Mech., 103(2-3), 205 (2002)
- Kim S, Namgung B, Ong PK, Cho YI, Chun KJ, Lim D, J. Mech. Sci. Technol., 23, 1718 (2009)
- Lee BK, Xue S, Nam J, Lim H, Shin S, Korea-Aust. Rheol. J., 23, 1 (2011)
- Lee BK, Alexy T, Wenby RB, Meiselman HJ, Biorheol., 44, 29 (2007)
- Lim HJ, Lee YJ, Nam JH, Chung S, Shin S, Rev. Sci. Instrum. 50, 096101 (2009)
- Lim HJ, Lee YJ, Nam JH, Chung S, Shin S, J. Biomech., 43, 546 (2010)
- Merrill EW, Gilliland ER, Cokelet G, Shin H, Britten A, Wells RE, J. Appl. Physiol., 18, 255 (1963)
- Merrill EW, Gilliland ER, Cokelet G, Shin H, Britten A, Wells RE, Biophys. J., 3, 199 (1963)
- Merrill EW, Rheology of blood, Physiol. Rev., 49, 863 (1969)
- Merrill EW, Cheng CS, Pelletier GA, J. Appl. Physiol., 26, 1 (1969)
- Morris CL, Smith II CM, Blackshear PL, Biophys J., 52, 229 (1987)
- Neu B, Meiselman HJ, Biophys. J., 83, 2482 (2002)
- Neumann FJ, Schmid-Schonbein H, Ohlenbusch H, Pflugers Arch., 408, 524 (1987)
- Picart C, Carpentier PH, Galliard H, Piau JM, Am. J. Physiol., 276, 771 (1999)
- Rampling MW, Meiselman HJ, Neu B, Baskurt OK, Biorheology, 41, 91 (2004)
- Reinhart WH, Singh A, Eur. J. Clin. Invest., 20, 458 (1990)
- Razavian SM, Del Pino M, Simon A, Levenson J, Hypertension, 20, 247 (1992)
- Replogle R, Herbert M, Merril EW, Circulation, 36, 148 (1967)
- Shin S, Ku Y, Park MS, Suh JS, Clin. Hemorheol. Microcirc., 30, 467 (2004)
- Shin S, Hou JX, Suh JS, Korea-Aust. Rheol. J., 19(2), 61 (2007)
- Shin S, Ku YH, Ho JX, Kim YK, Suh JS, Singh M, Clin Hemorheol Microcirc., 36, 253 (2007)
- Shin S, Nam JH, Hou JX, Suh JS, Clin Hemorheol Microcirc., 42, 117 (2009)
- Snabre P, Bitbol M, Mills P, Biophys. J., 5, 795 (1987)
- Spengler MI, Svetaz MJ, Leroux MB, Bertoluzzo SM, Carrara P, Van Isseldyk F, Petrelli D, Parente FM, Bosch P, Clin Hemorheol Microcirc., 47, 279 (2011)
- Volger E, Schmid-Schonbein H, Gosen J, Klose HJ, Kline KA, Pflugers Arch., 354, 319 (1975)
- Weed RI, LaCelle PL, Merrill EW, J. Clin. Invest., 48, 795 (1969)
- Xue S, Lee BK, Shin S, Clin Hemorheol Microcirc., 55, 231 (2013)
- Zydney AL, Oliver III JD, Colton CK, J. Rheol., 35, 1639 (1991)