A new technique, electro-hydrodynamic nanowire (e-NW) lithography, is demonstrated for the rapid, inexpensive, and efficient fabrication of graphene nanoribbons (GNRs) on a large scale while simultaneously controlling the location and alignment of the GNRs. A series of interesting GNR architectures, including parallel lines, grids, ladders, and stars are produced. A sub-10-nm-wide GNR is obtained to fabricate field-effect transistors that show a room-temperature on/off current ratio of ca. 70.