A ThermoGravimetric Analyser with Differential Scanning Calorimeter (TGA-DSC) was modelled and simulated to evaluate heat transfer to the sample and the internal operation of the equipment. For this purpose, a mesh was generated based on a CAD design of the real geometry, and several models were applied. Some of these models were built into the CFD commercial software, and some were developed by the authors. Realistic boundary conditions were applied, and a control system based on PID operation was implemented to manage the heat released by an electrical resistance, similar to the real equipment. Finally, simulation results were obtained and contrasted with real data. (c) 2012 Elsevier Ltd. All rights reserved.