In this paper, the optimal filtering problem is investigated for a class of networked systems in the presence of stochastic sensor gain degradations. The degradations are described by sequences of random variables with known statistics. A new measurement model is put forward to account for sensor gain degradations, network-induced time delays as well as network-induced data dropouts. Based on the proposed new model, an optimal unbiased filter is designed that minimizes the filtering error variance at each time-step. The developed filtering algorithm is recursive and therefore suitable for online application. Moreover, both currently and previously received signals are utilized to estimate the current state in order to achieve a better accuracy. A numerical simulation is exploited to illustrate the effectiveness of the proposed algorithm. (c) 2014 Elsevier Ltd. All rights reserved.