Photocatalytic oxidation over titanium dioxide is a promising technique for decomposition of hazardous compounds effectively. This paper reports the photocatalytic oxidation of methyl ethyl ketone (MEK) in air over three commercialized TiO2 catalysts, namely PC500, PC50, and P25. The photocatalytic activity of catalysts was evaluated in a fluidized bed reactor under UV-A light, which was supplied by light emitting diodes (LEDs). Pure anatase titania with remarkable high surface area, PC500, yielded the highest reaction rate. The high surface area of PC500 titania compensates the faster recombination of charge carries and maintains the superior activity under steady state condition. From quantum yield calculations, the use of the most active titania under low intensity of UV light was determined as preferable condition to carry out MEK photocatalytic oxidation. (C) 2013 Elsevier B.V. All rights reserved.