A simulation for the reaction integrated adsorption of trienzymatic synthesized laminaribiose was created, based on three individual enzymatic kinetics and equilibrium data from pure substance measurements. A discontinuous integration of reaction and adsorption was able to increase the yield by one third. A continuous adsorption with a cyclic transfer of loaded and replacement with fresh adsorbent can increase the yield by even 2.4 times. However, if the replacement cycle of the adsorbent is too short, the discharge of intermediates results in a reduced product formation.