Chemistry Letters, Vol.43, No.5, 678-680, 2014
Nitronyl Nitroxide as a Coupling Partner: Pd-Mediated Cross-coupling of (Nitronyl nitroxide-2-ido)(triphenylphosphine)gold(I) with Aryl Halides
A cross-coupling reaction using nitronyl nitroxide (NN) as a coupling partner was developed: Refluxing a mixture of [Au-I(NN-2-ido)(PPh3)] and aryl iodide (Ar-I) in THF in the presence of 10 mol % [Pd(PPh3)(4)] produced a cross-coupling product NN-Ar in a high yield. This method allowed the direct introduction of the NN radical onto various poly- and heterocyclic aromatic rings.