Energy use per square foot from science research labs is disproportionately higher than that of other rooms in buildings on campuses across the nation. This is partly due to labs' use of energy intensive equipment. However, laboratory management and personnel behavior may be significant contributing factors to energy consumption. Despite an apparent increasing need for energy conservation in science labs, a systematic investigation of avenues promoting energy conservation behavior in such labs appears absent in scholarly literature. This paper reports the findings of a recent study into the energy conservation knowledge, attitude and behavior of principle investigators, laboratory managers, and student lab workers at a tier 1 research university. The study investigates potential barriers as well as promising avenues to reducing energy consumption in science laboratories. The findings revealed: (1) an apparent lack of information about options for energy conservation in science labs, (2) existing operational barriers, (3) economic issues as barriers/motivators of energy conservation and (4) a widespread notion that cutting edge science may be compromised by energy conservation initiatives. (C) 2012 Elsevier Ltd. All rights reserved.