This paper explores the relationship between bioenergy, rural development and related innovation processes in two case studies (Emilia Romagna in Italy-and Norway), for a better understanding of the impacts of different policy regimes on bioenergy innovation. Regional innovation systems theory is used to explain the results emerging from the case studies and to identify the presence of potential elements for innovation. We used policy and relevant literature analysis and a grounded approach based on semi-structured interviews of relevant actors involved in the local bioenergy system. The main findings show that the case studies present consistent differences in terms of policy instruments and socio-political dynamics. Emilia Romagna has major weaknesses and threats that hinder innovation, but some positive potential elements for the future. Norway presents stronger local elements for innovation within local bioenergy systems, such as the employment of local resources and knowledge, but critical market and policy features that threaten further innovation developments. The conclusion draws on the comparative analysis to discuss policy implications of the study. (C) 2014 Elsevier Ltd. All rights reserved.