화학공학소재연구정보센터
Journal of Chemical and Engineering Data, Vol.59, No.3, 649-652, 2014
Thermodynamics of Fluconazole Solubility in Various Solvents at Different Temperatures
The solubility of Fluconazole in pure methanol, ethanol, propan-1-ol, butane-1-ol, chloroform, tetrahydrofuran, and 1,4-dioxane was measured by gravimetric method over a temperature range (298.15 to 323.15) K at atmospheric pressure. The solubility increases nonlinearly with temperature in all seven solvents. The experimental data were correlated with a modified Apelblat equation. The calculated results show good agreement with the experimental data.