Anaerobic digestion of Taihu blue algae was tested in laboratory scale, continuous feed digesters (hydraulic retention time 10 days) at 35 degrees C and various organic loading rates (OLR). The methane production and biomass digestion performed well at OLR below 4.00 gVS L-1 d(-1) but deteriorated as OLR increased due to the increased ammonia concentration, causing inhibition mainly to acetate and propionate degradation. Supplementing corn straw as co-feedstock significantly improved the digestion performance. The optimal C/N ratio for the co-digestion was 20:1 at OLR of 6.00 gVS L-1 d(-1). Methane yield of 234 mL CH4 gVS(-1) and methane productivity of 1404 mL CH4 L-1 d(-1) were achieved with solid removal of 63%. Compared with the algae alone, the methane productivity was increased by 46% with less accumulation of ammonia and fatty acids. The reactor rate-limiting step was acetate and propionate degradation. (C) 2013 Elsevier Ltd. All rights reserved.