This study proposes specific experiments to investigate the effect of nanoparticle wetting ability on gas-liquid mass transfer. A mass transfer experiment of CO2 absorption in a Ca(OH)(2)-CaCO3 system was carried out in a membrane dispersion microreactor. The effects of hydrophobicity and concentration of particles were investigated, and the mass transfer coefficient was experimentally determined. A mathematical model was developed to predict mass transfer from the gas-liquid interface and the bulk phase. First, the effects on interfacial mass transfer were quantified based on the coverage ratio of the nanoparticles on the interfacial surface. Second, in the bulk phase, the diffusion coefficient was modified based on the viscosity of suspensions with nanoparticles at the same concentration. The calculated results demonstrate that the model can accurately predict mass transfer performance at different particle hydrophobicities and concentrations. (C) 2014 Elsevier Ltd. All rights reserved.