In the present paper, we describe a new thermal-insulating facade system for newly constructed and renovated buildings, based on heat-insulating panels with ventilated channels. The calculated data on thermal resistances of heat-insulating panels and on the reduced thermal resistances of brick walls with an external facade system, formed by the panels with ventilated channels, are reported as a function of panel thickness. Heat transfer performance uniformity factors of brick walls with different numbers of anchors used for mounting a panel on the brick wall are determined. The calculations show that the heat transfer performance uniformity factors of ventilated panels can be substantially increased in comparison with similar factors for traditional ventilated facade systems. Non-stationary thermal and moisture calculations of newly constructed and renovated buildings with brick outer walls were carried out to determine the humidity dynamics of heat-insulating and structural wall layers over a period of three years. The calculations prove that the examined configuration of ventilated channels is capable of providing for low moisture content and good heat-insulating properties of the walls. Photos and thermograms of building facades, thermally insulated with ventilated channels, are presented. (C) 2014 Elsevier B.V. All rights reserved.