A phosphorus-containing flame retardant, 5,5-dimethyl-1,3,2-dioxaphosphorinane-2-(2,4,6-tribromophenoxy)-2-oxide(DPDMO), was synthesized successfully and characterized by elemental analysis (EA), mass spectra (MS), infrared spectroscopy (FT-IR) and nuclear magnetic resonance (H-1 NMR and C-13 NMR). The melting point and the enthalpy of fusion of DPDMO were measured by differential scanning calorimeter (DSC), and the thermal stability of DPDMO was obtained by thermogravimetric analysis (TGA). The solubility of DPDMO in selected solvents could be achieved by a gravimetric method. The experimental data were correlated with some thermodynamic models, such as the empirical equation and the Scatchard-Hildebrand, Wilson, nonrandom two liquid (NRTL), universal quasi chemical (UNIQUAC), and Buchowski-Ksiazaczak (lambda h) equation. The results show that the calculated values indicated good agreement with the experimental data. (C) 2013 Elsevier B.V. All rights reserved.