The vapour pressures of liquid mixtures 3,5- and 2,6-dimethylpyridine (or lutidines) with cyclohexane were measured by a static method in the range of 283.15-353.15K. The pure components vapour pressures data and those of corresponding mixtures were correlated using Antoine type equation. Data reduction by Barker's method provides correlation for excess molar Gibbs energy G(E). The excess molar enthalpies H-E of binary liquid mixtures of 3,5- and 2,6-dimethylpyridine with cyclohexane were measured at 303.15 K using a Calvet type microcalorimeter, C80 Setaram. The experimental results, along with our previous data of G(E) and H-E [1,2] are used for estimating interaction parameters in DISQUAC, an extended quasi-chemical group contribution model [3]. (C) 2014 Elsevier B.V. All rights reserved.