The effects of temperature, pressure, dissolved carbon dioxide and shear rate on the rheological response of bitumen are investigated by using the reduced variable method at the temperature range of -10 degrees C to 180 degrees C and pressures up to 15 MPa. A state of the art pressure cell set-up was utilized with a stress/strain controlled rheometer ( Anton-Paar, MCR-501) to collect the experimental data on the Athabasca bitumen-CO2 mixture. The double-log model is found to be the most accurate equation in describing the effect of temperature on the viscosity of bitumen over a wide range of temperature while the Barus model with the temperature-dependent parameter is found to be the most appropriate correlation to represent the effect of pressure. Excluding the effect of overhead pressure, the Fujita-Kishimato equation, resulting from the free volume concept modelling, is employed to account for the effect of dissolved CO2 on the viscosity of the bitumen-CO2 mixture more precisely. Moreover, a psuedoplastic model with a zero-shear viscosity is more rational to consider the effect of shear rate on the flow properties of the bituminous mixtures. The experimental conditions are carefully considered to avoid introducing flow instabilities into the mixture. It is demonstrated that the rheological properties of bitumen are more sensitive to the variables at lower temperatures. (C) 2013 Elsevier Ltd. All rights reserved.