화학공학소재연구정보센터
International Journal of Heat and Mass Transfer, Vol.60, 591-597, 2013
Non-Fourier bio heat transfer modelling of thermal damage during retinal laser irradiation
Study of non-Fourier energy transport is important in various biomedical applications, in the understanding of heat transfer in biological tissues. One such biomedical application that involves non-Fourier heat conduction is laser irradiation of the retina, where a high heat flux is typically applied for a short period of time. In the present study, retinal laser irradiation is analysed using the dual phase lag model for heat conduction. A simplified one-dimensional model of the human eye with seven layers is used in the simulation. The laser heating is modelled as a volumetric heat source and the respective magnitudes are calculated based on the absorptivities of the various layers. Apart from the temperature distribution, the damage distribution is also computed using the Arrhenius damage integral approach. The effect of the two phase lags tau(q) and tau(T) on the temperature and damage distributions are analysed. Small tau(T)/tau(q) ratios (<= 0.01) indicate a thermal wave like behaviour, which diminishes as the ratio increases (i.e. for tau(T)/tau(q) >= 0.1). The results are also compared with corresponding results from the Fourier model. Choroidal blood perfusion rate is found to have no significant effect on the unsteady temperature and damage distributions. (C) 2013 Elsevier Ltd. All rights reserved.