Carbon dioxide removal from the catalyst sites is critical to ensure high power output operation of direct methanol fuel cell (DMFC). In this work, a novel anode which contains water-proof oil, dimethyl silicon oil (DMS) was prepared for preventing liquid sealing effect (LSE) to CO(2). The novel electrode displays outstanding preventing LSE capability than a conventional PtRu/C electrode. The success of the novel anode in preventing LSE is due to DMS, in which the solubility and diffusion coefficient of CO(2) are much higher than that in methanol-water solution, supplying an unoccupied channel for CO(2) transportation. (C) 2009 International Association for Hydrogen Energy. Published by Elsevier Ltd. All rights reserved.