In this study, the hydrogen selling price from ethanol steam reforming has been estimated for two different production scenarios in the United States, i.e. central production (150,000 kg H(2)/day) and distributed (forecourt) production (1500 kg H(2)/day), based on a process flowchart generated by Aspen Plus' including downstream purification steps and economic analysis model template published by the U.S Department of Energy (DOE) [1]. The effect of several processing parameters as well as catalyst properties on the hydrogen selling price has been evaluated. $2.69/kg is estimated as the selling price for a central production process of 150,000 kg H(2)/day and $4.27/kg for a distributed hydrogen production process at a scale of 1500 kg H(2)/day. Among the parameters investigated through sensitivity analyses, ethanol feedstock cost, catalyst cost, and catalytic performance are found to play a significant role on determining the final hydrogen selling price. (C) 2009 Professor T. Nejat Veziroglu. Published by Elsevier Ltd. All rights reserved.