The influence of natural gas (NG) on the auto-ignition behavior of hydrogen (H-2)/nitrogen (N-2) fuel jets injected into a vitiated cross-flow was studied at conditions relevant for practical combustion systems (p = 15 bar, Tcross-flow = 1173 K). In addition, the flame stabilization process following auto-ignition was investigated by means of high-speed luminosity and shadowgraph imaging. The experiments were carried out in an optically accessible jet in cross-flow (JICF) test section. In a H-2/NG/N-2 fuel mixture, the fraction of H-2 was stepwise increased while keeping the N-2 fraction approximately constant. Two different jet penetration depths, represented by two N-2 fraction levels, were investigated. The results reveal that auto-ignition kernels occurred even for the lowest tested H-2 fuel fraction (X-H2/NG = X-H2/(X-H2 + X-NG) = 80%), but did not initiate a stable flame in the duct. Increasing X-H2/NG decreased the distance between the initial position of the auto-ignition kernels and the fuel injector, finally leading to flame stabilization. The H-2 fraction for which flame stabilization was initiated depended on jet penetration; flame stabilization occurred at lower H-2 fractions for the higher jet penetration depth (X-H2/NG = 91% compared to 96%), revealing the influence of different flow fields and mixing characteristics on the flame stabilization process. It is hypothesized that the flame stabilization process is related to kernels extending over the duct height and thus altering the upstream conditions due to considerable heat release. This enabled subsequent kernels to occur close to the fuel injector until they could finally stabilize in the recirculation zone of the jet lee. Copyright (C) 2013, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.