This paper is assessing the hydrogen production from bioethanol at industrial scale (100000 Nm(3)/h hydrogen equivalent to 300 MW thermal) with carbon capture. Three carbon capture designs were investigated, one based on pre-combustion capture using chemical gas-liquid absorption and two based on chemical looping (one based on syngas and one using direct bioethanol looping). The carbon capture options were compared with the similar designs without carbon capture. The designs were simulated to produce mass and energy balances for quantification of key performance indicators. A particular accent is put on assessment of reforming technologies (steam and oxygen-blown autothermal reforming) and chemical looping units, process integration issues of carbon capture step within the plant, modelling and simulation of whole plant, thermal and power integration of various plant sub-systems by pinch analysis. The results for chemical looping designs (either syngas-based or direct bioethanol) show promising energy efficiency coupled with total carbon capture rate. Copyright (C) 2014, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.