Based on experimental investigations the present study evaluates instability and heat transfer phenomenon under condition of periodic flow boiling of water and ethanol in parallel triangular micro-channels. Tests were performed in the range of hydraulic diameter 100-220 mu m, mass flux 32-200 kg/m(2)s, heat flux 120-270 kW/m(2), vapor quality x = 0.01-0.08. The period between successive events depends on the boiling number and decreases with an increase in the boiling number. The initial film thickness decreases with increasing heat flux. When the liquid film reached the minimum initial film thickness CHF regime occurred. Temporal variations of pressure drop, fluid and heater temperatures were periodic. Oscillation frequency is the same for the pressure drop, for the fluid temperature at the outlet manifold, and for the mean and maximum heater temperature fluctuations. All these fluctuations are in phase. The CHF phenomenon is different from that observed in a single channel of conventional size. A key difference between micro-channel heat sink and single conventional channel is amplification of parallel-channel instability prior to CHF. The dimensionless experimental values of the heat transfer coefficient are presented as the Nusselt number dependence on the Eotvos number and the boiling number. (c) 2006 Elsevier Ltd. All rights reserved.