화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korea Polymer Journal, Vol.3, No.2, 71-75, October, 1995
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Synthesis, Characterizatio and Biological Activity of Furan-Maleic Anhydride-Vinylacetate Terpolymer by Thermal Copolymerization of 3,5-Dioxo-4,10-dioxatricyclo[5.2.02,6]dec-8-ene and Vinylacetate
Jeong JG, Ha CS, Cho WJ
copolymerizations of 3,5-dioxo-4,10-dioxatricyclo[5.2.02,6]dec-8-ene(DDTD) with vinylacetate(VAc) were carried out in 2-butanone using AIBN as an initiator at 50℃ for 48 hrs. IR, 1H-NMR and 13C-NMR spectra of polymer obtained by a copolymerization were consistent with those of furan-maleic anhydride-vinylacetate terpolymer[terpoly(F-MAH-HAc)] which was prepared by terpolymerization of corresponding monomers such as furan(F), maleic anhydride(MAH) and vinylacetate(VAc).Prepared terpoly(F-MAH-VAc) showed polyelectrolyte viscosity behavior at low concentration in water or DMF. Average molecular weight of terpoly(F-MAH-VAc)s prepared under initiator concentration of 1,4 and 8 mol% were 23,400, 19,500 and 7,200, respectively. NK activities of terpoly(F-MAH-VAc) and 5-fluorouracil(5-FU) were evaluated in vitro. The NK activity of terpoly(F-MAH-VAc) was better than that of 5-FU.
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