We introduce a fast, easy and reliable methodology, using a stirred reactor, to equilibrate carbon dioxide with brine and measure the solubility of carbon dioxide in the aqueous phase at high pressure (9 MPa) and elevated temperature (33,50 and 70 degrees C) conditions at the litre scale. The solubility of carbon dioxide in brine was measured using an isothermal depressurization method and compared with data in the literature. This methodology can be used in petroleum engineering, carbon storage and chemical engineering applications. (C) 2011 Elsevier B.V. All rights reserved.