Through-Process modelling (TPM) of microstructure evolution during thermo-mechanical processing of sheet produced from direct chill (DC) cast non-heat treatable aluminium alloys is discussed. In a companion paper [1] the upstream processes of casting and homogenisation were dealt with, whereas the present paper focuses on the downstream deformation and annealing steps. Some recent advances in relevant model development are reviewed, and the important microstructural descriptors and their interactions are outlined. Together with two application examples - coiling of hot strip, and cold rolling of foil - current knowledge gaps in theory and modelling capability are highlighted.