In this paper, the unsteady flow of a nanofluid squeezing between two parallel plates is investigated. The Adomian Decomposition Method (ADM) is used to solve this problem. The base fluid is water containing different kinds of nanoparticles namely copper, silver, alumina and titanium oxide. The effective thermal conductivity and viscosity of the nanofluid are calculated using the Maxwell-Garnetts (MG) and Brinkman models, respectively. The analytical investigation is carried out for various governing parameters such as the squeeze number, nanoparticle volume fraction and Eckert number. The results show that for the case in which two plates are moving together, the Nusselt number increases with increase of nanoparticle volume fraction and Eckert number while it decreases with growth of the squeeze number. (C) 2013 Elsevier B.V. All rights reserved.