Separation of Chemically Similar Molecules by Molecular Recognition

Jae-Min Hong

Journal of Industrial and Engineering Chemistry, Vol.4, No.3, 226-230, September, 1998

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Separation of Chemically Similar Molecules by Molecular Recognition

Jae-Min Hong^†

Electronic Materials and Devices Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea

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A very thin layer of molecularly imprinted polymer (MIP) membrane was prepared for the separation of theophylline and caffeine which are chemically identical except one methyl group. Permeation characteristics of this membrane were affected by its morphology or crosslinking density. Theophylline imprinted membrane showed high selectivity for theophylline and caffeine imprinted membrane was caffeine selective.

Keywords:molecular recognition;membrane;separation

[References]

Paul DR, Polymeric Gas Separation Membranes, CRC Press, Ann Arbor (1994)
Wullf G, Polymeric Reagents and Catalysts, ACS Symposium Series, 308, Washington D.C., ACS, pp. 186-230 (1986)
Shea KJ, Sasaki DY, J. Am. Chem. Soc., 113, 4109 (1991)
Mosbach K, Trends Biochem. Sci., 19, 9 (1994)
Andersson LI, OShannessy DJ, Mosbach K, J. Chromatogr., 513, 167 (1990)
Wulff G, Schauhoff S, J. Org. Chem., 56, 395 (1991)
Andersson LI, Mosbach K, Makromol. Chem. Rapid Commun., 10, 491 (1989)
Fischer L, J. Am. Chem. Soc., 113, 9358 (1991)
Shea KJ, Sasaki DY, J. Am. Chem. Soc., 111, 3442 (1989)
Shea KJ, Stoddard GJ, Sasaki DY, Macromolecules, 22, 4304 (1989)
OShannessy DJ, Ekberg B, Andersson LI, Mosbach K, J. Chromatogr., 470, 391 (1989)
Robinson DK, Mosbach K, J. Chem. Soc.-Chem. Commun., 969 (1989)
Vlatakis G, Andersson LI, Muller R, Mosbach K, Nature, 361, 645 (1993)
Hedberg E, Winquest F, Lundstorm I, Anderson LI, Mosbach K, Sens. Actuators A-Phys., 37-38, 796 (1993)
Liu C, Martin CR, Nature, 352, 50 (1991)
Kang YS, Hong JM, Jang J, Kim UY, J. Membr. Sci., 109(2), 149 (1996)
Hong JM, Kang YS, Jang J, Kim UY, J. Membr. Sci., 109(2), 159 (1996)
Noble RD, Pellegrino JJ, Chem. Eng. Prog., 85, 58 (1989)

[Referenced By]

[Related Articles]

[1] Paul DR, Polymeric Gas Separation Membranes, CRC Press, Ann Arbor (1994)

[2] Wullf G, Polymeric Reagents and Catalysts, ACS Symposium Series, 308, Washington D.C., ACS, pp. 186-230 (1986)

[3] Shea KJ, Sasaki DY, J. Am. Chem. Soc., 113, 4109 (1991)

[4] Mosbach K, Trends Biochem. Sci., 19, 9 (1994)

[5] Andersson LI, OShannessy DJ, Mosbach K, J. Chromatogr., 513, 167 (1990)

[6] Wulff G, Schauhoff S, J. Org. Chem., 56, 395 (1991)

[7] Andersson LI, Mosbach K, Makromol. Chem. Rapid Commun., 10, 491 (1989)

[8] Fischer L, J. Am. Chem. Soc., 113, 9358 (1991)

[9] Shea KJ, Sasaki DY, J. Am. Chem. Soc., 111, 3442 (1989)

[10] Shea KJ, Stoddard GJ, Sasaki DY, Macromolecules, 22, 4304 (1989)

[11] OShannessy DJ, Ekberg B, Andersson LI, Mosbach K, J. Chromatogr., 470, 391 (1989)

[12] Robinson DK, Mosbach K, J. Chem. Soc.-Chem. Commun., 969 (1989)

[13] Vlatakis G, Andersson LI, Muller R, Mosbach K, Nature, 361, 645 (1993)

[14] Hedberg E, Winquest F, Lundstorm I, Anderson LI, Mosbach K, Sens. Actuators A-Phys., 37-38, 796 (1993)

[15] Liu C, Martin CR, Nature, 352, 50 (1991)

[16] Kang YS, Hong JM, Jang J, Kim UY, J. Membr. Sci., 109(2), 149 (1996)

[17] Hong JM, Kang YS, Jang J, Kim UY, J. Membr. Sci., 109(2), 159 (1996)

[18] Noble RD, Pellegrino JJ, Chem. Eng. Prog., 85, 58 (1989)