This paper develops an overall methodology for investigating the thermal and power behaviors of semi-transparent single-glazed photovoltaic window for office buildings in Hong Kong. In order to estimate its overall energy performance, this study is conducted in terms of total heat gain, output power and daylight illuminance. Three simulation models are established, including one-dimensional transient heat transfer model, power generation model and indoor daylight illuminance model. A typical office room reference is chosen as case study, and the weather data from 2003 to 2007 from the Hong Kong Observatory are used as the simulation inputs. By incorporating the simulation results, the overall energy performance can be evaluated in terms of electricity benefits corresponding to five orientations of the studied typical office. The priority of office orientation considering overall energy performance is: south-east, south, east, south-west and west. The findings show that thermal performance is the primary consideration of energy saving in the entire system whereas electricity consumption of artificial lighting is the secondary one. The overall annual electricity benefits are about 900 kWh and 1300 kWh for water-cooled and air-cooled air-conditioning systems respectively. The application of semi-transparent PV glazed window can not only produce clean energy, but also reduce building energy use by reducing the cooling load and electrical lighting requirements, which definitely benefits our environmental and economic aspects. (C) 2012 Elsevier Ltd. All rights reserved.