An especial open thermosyphon device used in high-temperature evacuated tubular solar collectors was designed. The indoor experimental research was carried out to investigate the thermal performance of the open thermosyphon using respectively the deionized water and water-based CuO nanofluids as the working liquid. Effects of filling rate, kind of the base fluid, nanoparticle mass concentration and the operating temperature on the evaporating heat transfer characteristics in the open thermosyphon were investigated and discussed. Experiment results show the optimal filling ratio to the evaporator is 60% and the thermal performance of the open thermosyphon increase generally with the increase of the operating temperature. Substituting water-based CuO nanofluids for water as the working fluid can significantly enhance the thermal performance of the evaporator and evaporating heat transfer coefficients may increase by about 30% compared with those of deionized water. The CuO nanoparticles mass concentration has remarkable influence on the heat transfer coefficient in the evaporation section and the mass concentration of 1.2% corresponds to the optimal heat transfer enhancement. (C) 2010 Elsevier Ltd. All rights reserved.