A catalytic plasma reactor was employed for the oxidation of isopropyl alcohol (IPA) classified as a volatile organic compound (VOC). Copper oxide (Cu : 0.5% (w/w)) supported on a multichannel porous ceramic consisting of α-Al2O3 was used as a catalyst, which was directly exposed to the plasma created in it. The effects of discharge voltage and reaction temperature on the concentrations of IPA and its byproducts were examined to understand the behavior of the catalytic plasma reactor. Without thermal insulation, the reactor temperature increased up to 120 ℃ at an applied voltage of 17 kV (discharge power : 28 W), and the IPA at a flow rate of 1 L min-1 (O2 : 10% (v/v); IPA : 1000 ppm) was completely removed. At temperatures below 120 ℃, however, besides the desirable product CO2, several unwanted byproducts such as acetone, formaldehyde and CO were also formed from IPA. On the other hand, when the reactor was thermally insulated, the plasma discharge increased the temperature up to 265 ℃ under the same condition and most of IPA was oxidized to CO2. Without loading CuO on the ceramic support, the plasma discharge in the thermally insulated reactor produced nearly equal amounts of CO2 and CO. On comparison, with the catalyst alone (temperature : 265 ℃), more than 70% of the removed IPA was simply converted into another type of VOC (acetone), indicating that the catalyst assisted by the plasma is more effective in the oxidation of IPA than that of the catalyst-alone process.