The enthalpies of the solution of beta-alanine in H2O + (methanol, ethanol, 1-propanol and 2-propanol) mixtures with alcohol content up to 0.4 mol fractions, have been determined calorimetrically at T = 298.15 K. The standard enthalpies of the solution and transfer of beta-alanine from water to aqueous alcohol have been calculated. The effect of structure properties of a mixed solvent on specified enthalpy characteristics of P-alanine is discussed. The enthalpy coefficients of pairwise interactions between beta-alanine and alcohol molecules have been computed. It has been found that these coefficients become increasingly positive in methanol, ethanol, 1-propanol, and 2-propanol sequence. A comparative analysis of thermodynamic characteristics of dissolution of beta-alanine and D,L-alpha-alanine in the mixtures studied has been made. Published by Elsevier B.V.